Meghan Teague, B.S., Lewis Kane, B.A. M.S., Shontal Behan, B.S
Angiosome theory was originally described in the context of plastic surgery and is commonly used to guide revascularization interventions in patients with ischemic foot wounds. This approach asserts that the foot and ankle can be divided into territories (angiosomes) that are each supplied by a primary vessel. Restoring arterial supply to an angiosome may therefore enhance wound healing. However, dynamic vascular anatomy, diseased patient populations, and varied wound distributions have made research on angiosomedirected revascularization strategies difficult to interpret. As a result, there is no current consensus regarding the validity of angiosome theory in ischemic wound therapy. Here we provide a brief overview of angiosome theory, the data supporting and refuting it, and potential approaches for future research.